Distinct modulation of allergic T cell responses by subcutaneous vs. sublingual allergen-specific immunotherapy
نویسندگان
چکیده
منابع مشابه
Economic evaluation of sublingual vs subcutaneous allergen immunotherapy.
BACKGROUND Sublingual allergen immunotherapy (SLIT) is a commonly used alternative route of administration to standard subcutaneous immunotherapy (SCIT) in Europe. Despite its wide use, the cost-effectiveness of SLIT vs SCIT has not been well established. OBJECTIVE To evaluate the cost and effectiveness of SLIT compared with SCIT in patients with allergic rhinoconjunctivitis during a 3-year s...
متن کاملLung-derived innate cytokines: new epigenetic targets of allergen-specific sublingual immunotherapy
Objective(s):Sublingual allergen-specific immunotherapy is a safe and effective method for treatment of IgE-mediated respiratory allergies; however, the underlying mechanisms are not fully understood. This study was planned to test whether sublingual immunotherapy (SLIT) can exert epigenetic mechanisms through which the airway allergic responses can be extinguished. Materials and Methods:BALB/c...
متن کاملA novel approach in allergen-specific immunotherapy: combination of sublingual and subcutaneous routes.
BACKGROUND Subcutaneous allergen-specific immunotherapy (SIT) has an early onset of action, whereas repeated injections and safety concerns have limited its use in the pediatric age group. Meanwhile, the improved safety profile of the sublingual route has been accepted as an alternative despite its relatively late onset of action. OBJECTIVE We sought to improve the efficacy and safety of SIT ...
متن کاملSubcutaneous and Sublingual Immunotherapy in Allergic Asthma in Children
This review presents up-to-date understanding of immunotherapy in the treatment of children with allergic asthma. The principal types of allergen immunotherapy (AIT) are subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT). Both of them are indicated for patients with allergic rhinitis and/or asthma, who have evidence of clinically relevant allergen-specific IgE, and significan...
متن کاملCorrigendum: Subcutaneous and Sublingual Immunotherapy in Allergic Asthma in Children
[This corrects the article on p. 82 in vol. 5, PMID: 28484690.].
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical & Experimental Allergy
سال: 2016
ISSN: 0954-7894
DOI: 10.1111/cea.12653